Deciding that he doesn't feel like discussing his adoptive father any further, Loki settles with giving a rather dramatic eyeroll at the second part of what Jane just said.

"In earnest. If humans still insist on treating other humans as criminals for what they feel, you really just should have let me just rule your planet." a bit of a playful jab, but with a serious issue for a background. An issue Loki at least hasn't encountered in this realm.